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Scientific Activity since January 2003.


ACE inhibition limits chronic injury of kidney transplant even with treatment started when lesions are established.

M. Noris, M. Mister, A. Pezzotta, N. Azzollini, P. Cassis, A. Benigni, E. Gagliardini, N. Perico, G. Remuzzi.

Submitted to Kidney International.


Two-hour post dose cyclosporine monitoring does not fit all in kidney transplantation.

D. Cattaneo, F. Gaspari, R. Caruso, E. Gotti, S. Murgia, A. Perna, N. Perico, G. Remuzzi.

Submitted to American Journal of Transplantation.


In transplantation blood cyclosporine levels soon after surgery determine whether or not an organ is rejection: insight from the MY.S.S. trial.

N. Perico, P. Ruggenenti, E. Gotti, F. Gaspari, D. Cattaneo, U. Valente, M. Salvadori, G. Segoloni, D. Donati, S. Sandrini, M. Ganeva, B.D. Dimitrov, G. Remuzzi.

Submitted to Kidney International.


Denditric cells (DC) genetically engineered to express dominant negative IKB kinase 2 (dnIKK2) induce T cell hyporesponse and development of regulatory T cells.

S. Aiello, R.A. Cavinato, M. Noris, L. Cassis, A. Benigni, S. Tomasoni, L. Longaretti, A. Pezzotta, M. Mister; N. Azzollini, P. Cravedi, G. Remuzzi.

Published on American Journal of Transplantation, vol 3:171, Abstract 77, 2003.



Grant for Research

Title:
"Donor peripheral blood mononuclear cells homing the thymus of recipients to induce graft tolerance"

Principal Investigator: Giuseppe Remuzzi
Grant: Roche Organ Transplantation Research Foundation (Switzerland)


Title:
"Donor stem cell infusion to induce allospecific graft tolerance"

Principal Investigator: Marina Noris
Grant: Roche Organ Transplantation Research Foundation (Switzerland)


Title:
"Trapianto combinato di cellule staminali e rene dallo stesso donatore per indurre tolleranza"

Principal Investigator: Marina Noris e Giuseppe Remuzzi
Grant: Fondazione Monzino (Italy)



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